The 100 mile White Rim trail loops around the Island in the Sky mesa top. Driving with a vehicle usually take 2 to 3 days.

Under favorable weather conditions, the White Rim Road is moderately difficult for high-clearance, four-wheel-drive vehicles. The steep, exposed sections of the Shafer Trail, Lathrop Canyon Road, Murphy Hogback, Hardscrabble Hill, and the Mineral Bottom switchbacks make the White Rim loop a challenging mountain bike ride, and require extreme caution for both vehicles and bikes during periods of inclement weather. During high water conditions on the Green River, sections of road on the west side can flood, making a complete loop impossible.